
Canine osteosarcoma treatment study.
Study details:
BluePearl is participating in a new clinical study to evaluate the efficacy of K9-ACV (autologous cancer vaccine) for the treatment of appendicular osteosarcoma (OSA) in dogs. Autologous cancer vaccines are produced from a dog's tumor and are therefore specialized to each individual patient.
Inclusion criteria:
- Dog is ≥ 1 year of age and greater or equal to 20 kilograms in weight.
- Dog is in good general health, with the exception of appendicular osteosarcoma, Stage IIB.
- Dog had cytologic and/or histologic confirmation of appendicular osteosarcoma, Stage IIB.
- Dog had a vaccine produced from its tumor according to the Outline of Production.
Exclusion criteria:
- Dog received concurrent or previous therapy (within 30 days) with immune-modulating drugs (e.g., cyclosporine, Apoquel, Cytopoint, prednisone, any chemotherapy, etc.)
- Dog received NSAIDs less than three days before immunization with the IVP.
- Dogs have received prior radiation therapy or bisphosphonates for their appendicular osteosarcoma.
- Dog has any uncontrolled medical condition that is likely to be disruptive to the intent of the study.
- Dog is known to be pregnant or likely to become pregnant during the study.
- Dog is lactating or intended for breeding during the study.
- Dog is participating in another therapeutic study.
- Dog is not available for the duration of the study.
Locations and contacts:
- Lafayette, CO: Caitlin Cowan, DVM, MS, DACVIM (Oncology); Kaleigh Peters, DVM, MS, DACVS-SA at 720.699.7766
- Pittsburgh, PA: Bridget Urie, DVM, MS, DACVIM (Oncology); Rebecca Newman, DVM, MS, DACVIM (Oncology) at 412.366.3400
- Tacoma, WA: Sharon Shor, DVM, MS, DACVIM (Oncology); Benjamin Perry, DVM, MS, DACVS-SA; Elizabeth Anglin, DVM, DACVS-SA at 253.474.0791
Duration of study:
Eight months.
Covered costs:
Dogs enrolled will have a significant portion of the surgical amputation costs covered, along with all charges for immunotherapy or chemotherapy-related treatment afterwards.