Clinical Studies

About BluePearl Science.

Founded by our dedicated clinicians, BluePearl Science operates with the following goals in mind:

Create a better future for pets.
In many cases, innovative diagnostic and treatment solutions and pharmaceuticals can save pets’ lives. Assessing the effectiveness of drugs can help protect and promote the lives of pets today, and tomorrow.

Share knowledge and expertise with the veterinary community.
We believe veterinarians can make the greatest impact when we work together. Performing clinical studies to gain knowledge about new medical treatment options is part of our service to the national veterinary community. Data from these studies are published in peer-reviewed literature, which allows all in the veterinary field to understand and benefit from the findings.

Advance the industry with new medical solutions.
Clinical studies are essential in the evolution of modern veterinary medicine. When new treatment or diagnostic options are engineered, we want to determine how they affect a pet’s medical condition and overall well-being.

Collaborate with primary care veterinarians.
BluePearl’s emergency and specialty clinicians share a common goal with general practice veterinarians – to provide effective, exceptional care for pets. Clinical studies open the door to further collaboration among veterinarians, resulting in more comprehensive treatment plans for pets.

Collaborate with pet families.
Pet patients may benefit from novel diagnostic or therapeutic options as part of BluePearl’s clinical studies program. BluePearl’s clinicians will involve the pet’s family in all medical decisions, offering information about both traditional and investigational approaches prior to treatment.

Leaders in advancing veterinary knowledge.

BluePearl clinicians are at the forefront of veterinary medicine. We’re proud to coordinate clinical studies in the private sector and contribute to the advancement of national veterinary knowledge from within our specialty and emergency facilities.

We perform clinical studies in highly active, fully operational hospitals equipped with advanced technology and diagnostic capabilities. Our diverse team of specialty clinicians rely upon their years of training and hands-on expertise to coordinate clinical studies aimed to treat complex pet conditions and illnesses, including lymphoma, diabetes, osteoarthritis, inflammatory bowel disease and more. The results of these studies are then published in peer-reviewed journals and available for all in the veterinary field.

Learn more about the BluePearl Science Institutional Review Board and meet our team of field leaders, scientists and preeminent veterinarians.

Clinical studies at BluePearl hospitals:

Clinical studies at our hospitals are often sponsored by our partners in industry and academia. Prior to approval of any clinical study, we require the following:

The study procedure, technology or drug being tested has a good chance of success.
The owners of the patients are fully aware of the study’s objectives, any potential risks resulting from the study, the names and contact information of the investigators and other pertinent details.
The owners of the patients have signed a written consent form for their pet to participate in the study. No pet can participate in a clinical study without the written consent of the pet’s owner.

If you believe that your pet may benefit from enrollment in a study, please contact your family veterinarian.

Current canine clinical studies:

Evaluating a Novel Immunotherapy Treatment for Malignant Oral Melanoma in Dogs
Locations: Malvern, PA; Overland Park, KS; Pittsburgh, PA
Purpose: This is a randomized, blinded, placebo-controlled trial of approximately 182 days in duration. Dogs will be randomly assigned to receive a novel immunotherapy or a placebo (non-active saline).
View Study

Cancer Detection Using Crystallography of Canine Nail Trimmings
Location: Malvern, PA
Purpose: A diagnostic procedure has been developed using x-ray diffraction technology to perform tissue crystallography on dog claw nails for the early and accurate detection of cancer as the first target pathology.
View Study

Cancer Lifetime Assessment Screening Study in Canines
Location: Malvern, PA
Purpose: Our screening test is a multi-cancer early detection (MCED) liquid biopsy test that may detect cancer with a simple blood draw.
View Study

Mars Petcare Biobank
Locations: Clearwater, FL; Brandon, FL; Tampa, FL
Purpose: By studying a pet’s health throughout its life, scientists will seek to identify potential signs of disease as well as new ways to help prevent or even predict illness.
View Study

TRIAD Study – The Dog Aging Project
Locations: Midtown, NY; Overland Park, KS; North Dallas, TX; Sandy Springs, GA
Purpose: To determine whether rapamycin increases the lifespan of companion dogs.
View Study

Effectiveness and Safety of Verdinexor for the Treatment of Lymphoma in Dogs
Location: Pittsburgh, PA
Purpose: To confirm the efficacy and safety of verdinexor for the treatment of lymphoma in dogs.
View Study

Identifying Drug Prediction and Risk Factors in Dogs with Mast Cell Tumors
Locations: Malvern, PA; Kirkland, WA; Levittown, PA; Cary, NC; Rockville, MD; Tampa, FL; Raleigh, NC
Purpose: To develop a test that will identify the best drugs to treat mast cell tumors (MCT) in dogs.
View Study

Current feline clinical studies:

Previous clinical studies.

Canine:

Acute Abdomen Syndrome – C-reactive protein (CRP)
Addison’s Disease – new medication
Arthritis
Atopic Dermatitis – new medication
Atopic Dermatitis – biomarkers in select breeds
B-Cell Lymphoma – chemotherapy protocol
Canine Lymphoma (Untreated) – evaluation with medication
Chemotherapy – evaluation with acupuncture and herbal medicine
Chemotherapy-Induced Diarrhea – new medication
Chronic Enteropathy – determine effects of dietary regulation
Congestive Heart Failure – treatment of associated pulmonary edema and cardiomegaly
Diabetes – new medication
Elbow Dysplasia/Osteoarthritis – pain management
Heart Disease – new medication
Hip Surgery or Limb Amputation – pain reduction
Hypothyroidism – new medication
Inflammatory Bowel Disease – new medication
Lymphoma – new oral drug
Lymphoma – feasibility study of lymphocyte collection from dogs with lymphoma
Lymphoma – clinical device to inject cancer drugs
Lymphoma, B-cell – clinical device to inject cancer drugs
Lymphoma – therapeutic agent
Lymphoma, T-cell – immunotherapy chemotherapy protocol
Lymphoma, T- and B-cell – MAb therapeutic treatment
Mast Cell Tumors – therapeutic agent
Melanoma and Mast Cell Tumors – immunotherapy

Oncology Appetite and Quality-of-Life Survey
Osteosarcoma – vaccine
Pain Control Post Cranial Cruciate Ligament or Medial Patellar Luxation Surgery – new medication
Pain Control Post Cranial Cruciate Ligament Surgery – new medication
Palladia® Chemotherapy-Induced Diarrhea – medication safety
Seizures – medication
Seizures Associated with Idiopathic Epilepsy – medications
Solid Tumors in Dogs – therapeutic agent
Soft Tissue Sarcomas – therapeutic agent
Splenic Hemangiosarcoma – compare medications
Thrombocytopenia – new platelet product
Transitional Cell Carcinoma – pain management